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Apex Safe DNA Loading Dye with Gel Stain replaces hazardous and mutagenic Ethidium Bromide (EtBr). It is supplied at 6X concentration and is added directly to the DNA samples before pipetting into gel wells. It is not required to add any stain to the gel or running buffer. After electrophoresis, view and document your results using a UV or Blue Light Illuminator. Compatible in both agarose and polyacrylamide gels, Apex Safe DNA Gel Stain emits green flourescence when bound to dsDNA or ssDNA and red flourescence when bound to RNA. It also offers better sensitivity than EtBr - detect as little as 0.1ng of DNA.
Apex Safe DNA products are considered safer than Ethidium Bromide. They are non-carcinogenic as determined by the Ames-test, with negative results in mouse primary spermatocycte chromosomal aberration tests and mouse marrow chromophilous erythrocyte micronucleus tests.